It is definitely possible to bring about a totally new mind.
…The ingredient - if I may use that word - which is absolutely necessary is the quality of affection and integrity. I don’t mean by integrity any form of pattern of belief, nor do I mean it as integrity according to the experience through which one has to live; but I mean that integrity that comes about when you begin to observe every movement of your own thought and when no thought is hidden. You do not wear a mask, you do not any longer pretend to be something other than what you actually are; and therefore there is no discipline, no fancy, no worship; and out of that comes the external sense of integrity I mean that kind of integrity, not the man who has belief and lives according to that belief, not the man who is sincere but with certain ideals, not the man who follows a certain discipline or tries to bring about an integration emotionally or intellectually. Such efforts do not bring out integrity. On the contrary, they increase conflict, misery.
Madras, India | 4th Public Talk 3rd December 1961